Cipro Ingredients and Composition

Cipro Information

Cipro Ingredients and Composition

Cipro (Ciprofloxacin hydrochloride) tablets and oral suspension are synthetic broad spectrum antimicrobial agents for oral administration. Ciprofloxacin hydrochloride, a fluoroquinolone is the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluora-1, 4-dihydro-4-oxa-7-(1-piperazinyl)-3-quinolinecarboxylic acid. It is a faintly yellowish to light yellow crystalline substance with a molecular weight of 385.8. Its empirical formula is C₁₇H₁₈FN₃O₃•HCl•H₂O.

Ciprofloxacin is 1-cyclopropyl-6-fluoro-1, 4-drhydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. Its empirical formula is C₁₇H₁₈FN₃O₃ and its molecular weight is 331.4 It is a faintly yellowish to light yellow crystalline substance.

Ciprofloxacin differs from other quinolones in that it has a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position.

Cipro film-coated tablets are available in 100-mg, 250-mg, 500-mg and 750-mg (ciprofloxacin equivalent) strengths. The inactive ingredients are starch, microcrystalline cellulose, silicon dioxide, crospovidone, magnesium stearate, hydroxypropyl methylcellulose, titanium dioxide, polyethylene glycol and water.

Cipro oral suspension is available in 5% (5 g ciprofloxacin in 100 ml) and 10% (10 g ciprofloxacin in 100 ml) strengths. Ciprofloxacin HCl oral suspension is a white to slightly yellowish suspension with strawberry flavor which may contain yellow-orange droplets. It is composed of ciprofloxacin microcapsules and diluent which are mixed prior to dispensing. The components of the suspension have the following compositions:

Cipto Microcapsules: Ciprofloxacin, polyvinylpyrrolidone, methacrylic acid copolymer, hydroxypropyl methylcellulose, magnesium stearate and Polysorbate 20.

Cipro Information