Denavir Side Effects

Denavir Information

Denavir Side Effects

In two double-blind placebo-controlled Denavir trials, 1516 patients were treated with Denavir (penciclovir cream) and 1541 with placebo. The most frequently reported Denavir side effect was headache, which occurred in 5.3% of the patients treated with Denavir and 5.8% of the placebo-treated patients. The rates of reported local adverse reactions are shown below. One or more local side effects were reported by 2.7% of the patients treated with Denavir and 3.9% of placebo treated patients.

Application site reaction

• Hypesthesia/Local anesthesia
• Taste perversion
• Pruritus
• Pain
• Rash (erythematous)
• Allergic reaction

Two studies, enrolling 108 healthy subjects were conducted to evaluate the dermal tolerance of 5% penciclovir cream (a 5-fold higher concentration than the commercial formulation) compared to vehicle using repeated occluded patch testing methodology. The 5% Denavir (penciclovir) cream induced mild erythema in approximately one-half of the subjects exposed an irritancy profile similar to the vehicle control in terms of severity and proportion of subjects with a response. No evidence of sensitization was observed.

As with any medication, you may experience additional unreported Denavir side effects.

Denavir Information