Famvir Ingredients and Composition
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Famvir Ingredients and Composition
Famvir contains famciclovir, an orally administered prodrug of the antiviral agent penciclovir. Chemically, famciclovir is known as 2-[2-(2-amino-9H-purin-9-yl)ethyl]-1,3-propanediol diacetate. Its molecular formula is C14H19N55O4 ; its molecular weight is 321.3. It is a synthetic acyclic guanine derivative.
Famciclovir, the active ingredient in Famvir, is a white to pale yellow solid. It is freely soluble in acetone and methanol, and sparingly soluble in ethanol and isopropanol. At 25°C famciclovir is freely soluble (>25% w/v) in water initially, but rapidly precipitates as the sparingly soluble (2-3% w/v) monohydrate. Famciclovir is not hygroscopic below 85% relative humidity. Partition coefficients are: octanol/water (pH 4.8) P=1.09 and octanol/phosphate buffer (pH 7.4) P=2.08.
Famvir Tablets for Oral Administration: Each white, film-coated tablet contains famciclovir. The 125 mg and 250 mg tablets are round; the 500 mg tablets are oval.
Inactive ingredients of Famvir Tablets are:
- hydroxypropyl cellulose
- hydroxypropyl methylcellulose
- lactose
- magnesium stearate
- polyethylene glycols
- sodium starch glycolate
- titanium dioxide
