Famvir Side Effects

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Famvir Side Effects

Immunocompetent Patients

The safety of Famvir has been evaluated in clinical studies involving 816 Famvir-treated patients with herpes zoster (Famvir, 250 mg t.i.d. to 750 mg t.i.d.); 528 Famvir-treated patients with recurrent genital herpes (Famvir, 125 mg b.i.d. to 500 mg t.i.d.); and 1,197 patients with recurrent genital herpes treated with Famvir as suppressive therapy (125 mg q.d. to 250 mg t.i.d.) of which 570 patients received Famvir (open-labeled and/or double-blind) for at least 10 months. Selected Famvir side effects are listed below:

Nervous System:

• Headache
• Paresthesia
• Migraine

Gastrointestinal:

• Nausea
• Diarrhea
• Vomiting
• Flatulence
• Abdominal Pain

Body as a Whole:

• Fatigue

Skin and Appendages:

• Pruritus
• Rash

Reproductive Female:

• Dysmenorrhea

HIV-lnfected Patients

In HIV-infected patients, the most frequently reported Famvir side effects (500 mg twice daily; n=150) and acyclovir side effects(400 mg, 5x/day; n=143), respectively, were headache (16.0 vs 15.4%), nausea (10.7 vs 12.6%), diarrhea (6.7 vs 10.5%), vomiting(4.7 vs 3.5%), fatigue (4.0 vs 2.1%), and abdominal pain(3.3 vs 5.6%).

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