Famvir Side Effects
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Famvir Side Effects
Immunocompetent Patients
The safety of Famvir has been evaluated in clinical studies involving 816 Famvir-treated patients with herpes zoster (Famvir, 250 mg t.i.d. to 750 mg t.i.d.); 528 Famvir-treated patients with recurrent genital herpes (Famvir, 125 mg b.i.d. to 500 mg t.i.d.); and 1,197 patients with recurrent genital herpes treated with Famvir as suppressive therapy (125 mg q.d. to 250 mg t.i.d.) of which 570 patients received Famvir (open-labeled and/or double-blind) for at least 10 months. Selected Famvir side effects are listed below:
Nervous System:
- Headache
- Paresthesia
- Migraine
Gastrointestinal:
- Nausea
- Diarrhea
- Vomiting
- Flatulence
- Abdominal Pain
Body as a Whole:
- Fatigue
Skin and Appendages:
- Pruritus
- Rash
Reproductive Female:
- Dysmenorrhea
HIV-lnfected Patients
In HIV-infected patients, the most frequently reported Famvir side effects (500 mg twice daily; n=150) and acyclovir side effects(400 mg, 5x/day; n=143), respectively, were headache (16.0 vs 15.4%), nausea (10.7 vs 12.6%), diarrhea (6.7 vs 10.5%), vomiting(4.7 vs 3.5%), fatigue (4.0 vs 2.1%), and abdominal pain(3.3 vs 5.6%).
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