Fioricet Side Effects
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Fioricet Side Effects
Frequently Observed and Mild Side Effects
The most frequently reported adverse reactions or side effects include:
- drowsiness
- light-headedness
- dizziness
- sedation
- shortness of breath
- nausea or vomiting (if it occurs without other symptoms of overdose)
- abdominal pain
- feeling of intoxication
Serious Fioricet Side Effects
These side effects should be reported to your doctor as soon as possible, and include:
- mild excitement (euphoria)
- depression
- mild confusion
- bloody or black stools
- bloody urine
- red pinpoints on skin
- painful or swollen glands
- unusual (mild) tiredness or weakness
- unusual bleeding or bruising
Contact a doctor immediately if you experience any of the following symptoms, and especially if you experience several together:
- bleeding sores on your lips
- chest pain
- fever
- large hive-like swellings on face or in mouth
- muscle cramping or pain
- thick or reddened skin
- scaly skin
- rash
- itching
- hives
- sores or ulcers in the mouth
- painful white spots in mouth
- sore throat
Infrequently Observed
All adverse events tabulated below are classified as infrequent.
Central Nervous: headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, sluggishness, seizure. Mental confusion, excitement or depression can also occur due to intolerance, particularly in elderly or debilitated patients, or due to overdosage of butalbital.
Autonomic Nervous: dry mouth, hyperhidrosis.
Gastrointestinal: difficulty swallowing, heartburn, flatulence, constipation.
Cardiovascular: tachycardia.
Musculoskeletal: leg pain, muscle fatigue.
Genitourinary: diuresis.
Miscellaneous: pruritus, fever, earache, nasal congestion, tinnitus, euphoria, allergic reactions. Several cases of dermatological reactions, including toxic epidermal necrolysis and erythema multiforme, have been reported.
The following adverse drug events may be borne in mind as potential effects of the components of this product. Potential effects of high dosage are listed in the
Fioricet Overdose section.
Acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis.
Caffeine:cardiac stimulation, irritability, tremor, dependence, nephrotoxicity, hyperglycemia.
Fioricet Drug Abuse and Dependence
Butalbital: Barbiturates may be habit-forming.
Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates. The average daily dose for the barbiturate addict is usually about 1500 mg. As tolerance to barbiturates develops, the amount needed to maintain the same level of intoxication increases; tolerance to a fatal dosage, however, does not increase more than two- fold. As this occurs, the margin between an intoxication dosage and fatal dosage becomes smaller. The lethaldose of a barbiturate is far less if alcohol is also ingested.
Major withdrawal symptoms (convulsions and delirium) may occur within 16 hours and last up to 5 days after abrupt cessation of these drugs. Intensity of withdrawal symptoms gradually declines over a period of approximately 15 days. Treatment of barbiturate dependence consists of cautious and gradual withdrawal of the drug.
Barbiturate-dependent patients can be withdrawn by using a number of different withdrawal regimens. One method involves initiating treatment at the patient's regular dosage level and gradually decreasing the daily dosage as tolerated by the patient.
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