Guggulsterone
Guggulsterone Information
Grown in India, Bangladesh, and Pakistan, Guggul is a tree which exudes a resinous sap out of incisions that are made in its bark. This resin has been used for centuries as part of India's traditional medicine called Ayurveda. In our modern world of advanced chemistry, this resinous sap is processed and purified, and then standardized for a given amount of its active constituents-Z and E Guggulsterones. These two compounds are plant sterols with a high degree of human bioactivity and have been shown in studies to affect many biological processes including thyroid metabolism, cholesterol management, and dermal (skin) function. In each of these areas, Guggulsterones were shown in studies to be highly effective modulators with near drug-like potency.
Acne suppression
With tetracycline, the percentage reduction in the inflammatory lesions was 65.2% as compared to 68% with the Guggulsterones.
The most potent Guggulsterone varieties are E and Z.
Natural Sources of Guggulsterone
Sap of the guggul tree (Commiphora mukul), grown in India, Bangladesh, and Pakistan.
How Does Guggulsterone Work?
Guggulsterones stimulate the thyroid gland, which in turn produces more thyroid hormones such as thyroxin. These thyroid hormones have a profound effect on the rate of metabolism including a direct catabolic effect on adipose tissue. Practically, this means that Guggulsterones will stimulate your thyroid to produce more thyroid hormones which in turn will raise your metabolic rate and burn more fat.
Guggulsterones increase the peripheral conversion of T4 into T3. Increasing the peripheral conversion of T3 is highly important because the thyroid only produces 20% of the body's T3. Most of the remaining 80% is derived from T4 through a conversion process that occurs in various target tissues, like skeletal muscle, for example.
How To Take Guggulsterone and Guggulsterone Dosage and Administration
Take about 30-60mg of Guggulsterone three times per day with meals.
Guggulsterone Side Effects
Guggulsterone Precautions and Contraindications
Guggulsterones may compete with some cholesterol reducing medications, so if you are on such medications you should consult a doctor before taking guggul. Likewise, you should consult a doctor if you have a thyroid disorder.
