Hydroxycitric Acid (HCA)
Hydroxycitric Acid (HCA) Information
Hydroxycitric acid (HCA) is the active ingredient in the herbal compound Garcinia cambogia. It should competitively inhibit the extramitochondrial enzyme adenosine triphosphate-citrate (pro-3S)-lyase. As a citrate cleavage enzyme that may play an essential role in de novo lipogenesis inhibition. As a result, G cambogia is claimed to lower body weight and reduce fat mass in humans.
Hydroxycitric acid is an 'additive' ingredient of many weight-loss drugs, and is promoted as an appetite suppressant. It is especially important in ephedra-free products as thermogenic weight-loss is nowhere near as efficient with only caffeine and aspirine being used.
However a study by Department of foods and Nutrition of the Purdue University in Indiana, showed no benefits of HCA over placebo being given to the control group. Both groups had comparable weight loss and appetites. Similar studies returned identical results.
While this was enough for some to dismiss HCA outright, there are now suggestions that the studies were not carried out with a sufficiently high a dosage of HCA. This should be around 1-5 grams per day. Also, improved potassium and potassium magnesium delivery systems are supposed to be more effective.
Ephedra - free Hydroxycut now claims to deliver substantial amounts of Citrimax HCA, that should be more than adequate to exploit any potential benefits of the compound. But remember - HCA is only one of Hydroxycut's active ingredients, so that the potential benefits will come from other active ingredients as well. Propaganda aside - Hydroxycut does seem to be one of the better products on the market.
Finally, HCA has not been shown to have any adverse side effects.
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