Imitrex Side Effects

Imitrex Information

Imitrex Side Effects

Serious cardiac events, including some that have been fatal, have occurred following the use of Imitrex (sumatriptan succinate) injection or tablets, and may be Imitrex side effects. These events are extremely rare and most have been reported in patients with risk factors predictive of CAD. Events reported have included coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular tachycardia, and ventricular fibrillation.

Significant hypertensive episodes, including hypertensive crises, have been reported on rare occasions in Imitrex (sumatriptan succinate) patients with or without a history of hypertension.

Incidence in Controlled Clinical Trials

The list below lists adverse events that occurred in placebo-controlled clinical trials in patients who took at least one dose of study drug. Only side effects that occurred at a frequency of 2% or more in any group treated Imitrex (sumatriptan succinate) tablets and were more frequent in that group than in the placebo group are included in the list. The Imitrex side effects cited reflect experience gained under closely monitored conditions of clinical trials in a highly selected patient population. In actual clinical practice or in other clinical trials, these frequency estimates may not apply, as the conditions of use, reporting behavior, and the kinds of patients treated may differ.

Treatment-Emergent Adverse Events Reported by at Least 2% of Patients in Controlled Migraine Trials

• Atypical Sensations
• aresthesia (all types)
• ensation warm/cold
• Pain and Other Pressure Sensations
• Chest: pain/ tightness/ pressure and/or heaviness
• Neck/ throat/jaw: pain/ tightness/ pressure
• Pain: location specified, pressure/ tightness/ heaviness
• Neurological: Vertigo
• Other: Malaise/ fatigue

Other Imitrex side effects that occurred in more than 1% of patients included nausea and/or vomiting, migraine, headache, hyposalivation, dizziness, and drowsiness/sleepiness.

Imitrex (sumatriptan succinate) tablets are generally well tolerated. Across all doses, most adverse reactions were mild and transient and did not lead to long-lasting effects. The incidence of adverse events in controlled clinical trials was not affected by gender or age of the patients. There were insufficient data to assess the impact of race on the incidence of adverse events.

Imitrex Information