Metabogenic Rapid Weight Loss Formula is an ephedrine-free fat-burner made by Active Health Laboratories. Since Metabogenic is ephedrine-free, it doesn't have any of the side-effects that make ephedrine-based products problematic.
Metabogenic contains a proprietary blend of thermogenic compounds that promotes thermogenesis or should otherwise helps you to stay on your diet. Each Metabogenic ingredient conforms to the dosages proven in clinical studies to produce the greatest thermogenic effects.
The most active ingredients in Metabogenic are synephrine and caffeine. These plant chemicals work by inducing thermogenesis (the production of heat), which speeds up your metabolism and burns calories. They also have an appetite-suppressing effect, so you feel less hungry and therefore eat less.
Citrus aurantium, used in Metabogenic, is the botanical name for a fruit known as zhi shi in traditional Chinese medicine and as bitter orange or sour orange in other countries. The unripe fruit contains synephrine - a chemical that is structurally related to ephedrine - as well as octopamine and tyramine. Like ephedrine, synephrine has the ability to increase metabolic rate and lipolysis (fat breakdown). Synephrine is also a mild appetite suppressant and an energy enhancer, which are all effects that a drug like Metabogenic aims at. (The Chinese use it to stimulate the chi, life energy.) But unlike ephedrine, synephrine has much less impact on the central nervous system. This makes it easier to tolerate for people who are sensitive to ephedrine. The effects of synephrine are greatly increased when it is combined with caffeine. Metabogenic contains 5 mg of synephrine alkaloids.
Green tea contains potent antioxidant compounds called polyphenols. There are four primary polyphenols in green tea. While all four appear to have protective value, epigallocatechin gallate (EGCG) occurs in the greatest amounts and has the strongest benefits. EGCG is an antioxidant that is several times more potent than vitamin E. It also prolongs the life of norepinephrine, which triggers thermogenesis. As a result, EGCG keeps the thermogenic process going for a longer period of time, boosting your metabolic rate and facilitating fat loss.
Caffeine has been shown to dramatically increase free fatty-acid levels, providing the body with a fuel source that it can use instead of the glycogen stored in your liver and muscles - this is why Metabogenic uses it. In fact, one study found a 100% increase in plasma free fatty acids after the subjects took 330 mg of caffeine.
At the same time, caffeine has been shown to increase adrenaline levels. This "fight-or-flight" hormone increases alertness and boosts energy levels, helping you to go through your daily tasks with less food intake. Most people experience a reduced appetite when their adrenaline levels are high, usually because they are focused on more essential tasks. With these two mechanisms, it's easy to understand why caffeine is used in Metabogenic and is important for jump-starting your weight-loss efforts.
The standardized root extract of Coleus forskohlii (also known as forskolin) is a powerful herbal compound indigenous to India and used in Ayurvedic medicine. Scientists have found that forskolin helps increase lean body mass, enhance metabolism, increase fat burning and stimulate thyroid activity.
Without getting too technical, forskolin promotes lean body mass by increasing levels of something called cyclic AMP (cAMP). The role of cAMP in the body is vital to weight loss. It triggers a chain of biochemical events in the body that results in increased metabolism, thermogenesis, and mechanisms that promote lean body mass.
Based on its powerful mechanism of action, a company called Sabinsa Corporation developed a patented, standardized extract of Coleus forskohlii root called ForsLean that is used in Metabogenic.
Most of the studies on alpha lipoic acid have been done with diabetics, who often have a problem with insulin sensitivity. These studies have found that this coenzyme can increase the body's sensitivity to insulin, reducing the amount of insulin that needs to be produced by the pancreas (or injected). Nondiabetics also produce alpha lipoic acid, so it stands to reason that it would promote better utilization of insulin for them as well. Alpha lipoic acid is also a potent antioxidant, helping to fight free-radical damage in the cells. Metabogenic uses it for these purposes.
Numerous studies have indicated that naringin prolongs the chemical activity of caffeine. Research published in the British Journal of Clinical Pharmacology found that the half-life of caffeine was extended by 31% when naringin was present in sufficient amounts. Studies of various citrus fruits have shown that grapefruit has by far the highest content of naringin. It is, in fact, what gives grapefruit its characteristic bitter taste.
L-tyrosine is the amino acid tyrosine in free (unbound) form, while acetyl-L-tyrosine is the same amino acid tied to an acetyl molecule. Both are bioavailable forms of tyrosine, an amino acid that plays an important role in human metabolism. It is the precursor to stimulatory neurotransmitters such as epinephrine, norepinephrine, dopamine and some of the thyroid hormones. All of these neurotransmitters and hormones play important roles in maintaining your metabolic rate. Logically, if you have a greater supply of these precursors, you can nudge your metabolism up a bit, helping you to shed unwanted pounds. Several studies have also shown that tyrosine increases the benefits of thermogenic supplements, in part by curbing appetite. Tyrosine appears to reduce stress and fatigue as well, putting you in a better state of mind and making it easier to stick to your diet and exercise program, while on your Metabogenic course.
Take 3 Metabogenic capsules before breakfast or morning exercise session and 3 more capsules before your afternoon meal. Do not take in the evening. Do not exceed 6 Metabogenic capsules per day. For best results, begin with half of the recommended dose (1 capsule three times per day) for the first week to assess your tolerance to the Metabogenic formulation.
As with any thermogenig weight-loss pill, you should consult your doctor before taking Metabogenic, especially if you have a previous history of health problems.
Like other synephrine/caffeine-based products on the market, Metabogenic will induce thermogenesis (raise your body's temperature) and cause you to burn more calories. Other Metabogenic results include: suppressing your appetite, preserving lean muscle mass, and increasing your energy levels. The tyrosine in the Metabogenic formulation is claimed to increase these benefits by further curbing appetite and reducing fatigue and stress levels.