Metabolife 356
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Metabolife 356 Information
Related Brand Names: Metabogenic
Metabolife 356 is the main thermogenic weight-loss pill of Metabolife International. Metabolife 356 contains a proprietary blend of guarana, ma huang, Siberian ginseng, ginger and seven other herbs. It also contains spirulina, lecithin, bovine complex, chromium picolinate, zinc, magnesium and vitamin E.
The most active ingredients in Metabolife 356 are ephedrine and caffeine. Like other ephedrine/caffeine-based products, Metabolife 356 works by inducing thermogenesis (the production of heat), which speeds up your metabolism and burns calories. It also has an appetite-suppressing effect, so you feel less hungry and therefore eat less.
Thus, Metabolife 356 works on two fronts:
- thermogenesis: 'speeding up' you metabolism, and making you burn more calories
- appetite suppression: making you eat less, and forcing the organism to mobilise the supplies it already posseses - ie. use up fat.
Metabolife 356 Ingredients and Composition
How Does Metabolife 356 Work?
Metabolife 356 contains a variety of nutrients that helps you to lose weight through different mechanisms. But the main ingredients that produce its fat-burning effects are ephedrine and caffeine. Studies have shown that when these ingredients are combined in fairly specific ratios - 200 mg caffeine to 20 mg ephedrine (two or three times daily) - the results are synergistic. In other words, the effects of each are greater than the sum of their individual effects.
Here is a breakdown of the individual ingredients in Metabolife 356 and what they do:
Ephedra in Metabolife 356
Ephedrine is the primary fat-burning chemical in the Ephedra sinica plant, from which it gets its name. Also known as ma huang, this plant has a long history of usage in Asian countries for the treatment of asthma and other bronchial conditions. A related chemical, pseudoephedrine, is also found in the plant and is an ingredient in many cold and flu remedies.
Ephedrine is a stimulant that works on the adrenergic receptors of the central nervous system. It has been shown to increase the level of dopamine, which is a precursor to both epinephrine and norepinephrine, which are vital neurotransmitters. Dopamine is also an important neurotransmitter around the hypothalamus, an area of the brain that is important for body arousal. Unlike caffeine, which exerts many of its benefits in muscle tissue, ephedrine appears to work primarily on the central nervous system.
Ephedrine inhibits the reuptake of norepinephrine, a hormone secreted by the medulla of the adrenal glands, that acts as a neurotransmitter. The sympathetic nervous system functions in response to short-term stress; hence norepinephrine increases the heart rate as well as blood pressure. Other actions of norepinephrine include increased glycogenolysis (the conversion of glycogen to glucose) in the liver, increased lipolysis (the conversion of fats to fatty acids) in adipose (fat) tissue, and relaxation of bronchial smooth muscle to open up the air passages to the lungs. All of these actions represent a mobilization of the body's resources in order to meet the stressful challenge; such a response is often termed the 'flight or fight' syndrome.
Basically, ephedra in Metabolife 356 keeps your body in 'combat' mode for extended periods of time, facilitating weight loss.
Ephedrine is an effective fat burner on its own, and when it is combined with caffeine, the effects are even greater. While the reasons for this are still not known, it is thought that caffeine has a "permissive" action on ephedrine, lowering the amounts needed to achieve its physiological effects. In other words, caffeine potentiates ephedrine's effect. The E/C studies that showed the greatest benefits used a 10:1 ratio of caffeine to ephedrine.
Caffeine in Metabolife 356
The caffeine source in Metabolife 356 is guarana seed extract. Guarana is a bushy tree that grows in the Amazon rainforest. Known botanically as Paullina cupana, it is almost as popular as coffee in Brazil. Guarana does not have as much acid as coffee, so it can be less irritating to the stomach than coffee can. Guarana also has epicathechin and proanthocyanidins, both of which are powerful antioxidants that help reduce free-radical damage in cells. Epicathechin is chemically related to epigallocatechin gallate (EGCG), which prolongs the life of norepinephrine. As a result, the epicathechin may keep the thermogenic process going for a even longer period of time, further boosting your metabolic rate and facilitating fat loss.
As far as fat burning is concerned, the primary active ingredient in guarana is caffeine. This plant chemical is rapidly absorbed by the body and remains in circulation for more than seven hours. Plasma concentrations reach a peak one hour after it is consumed. It is then slowly metabolized, with a half-life of four to six hours.
Caffeine has been shown to dramatically increase free fatty-acid levels, providing the body with a fuel source that it can use instead of the glycogen stored in your liver and muscles. In fact, one study found a 100% increase in plasma free fatty acids after the subjects took 330 mg of caffeine.
At the same time, caffeine has been shown to increase adrenaline levels. This "fight-or-flight" hormone increases alertness and boosts energy levels, helping you to go through your daily tasks with less food intake. Most people experience a reduced appetite when their adrenaline levels are high, usually because they are focused on more essential tasks. With these two mechanisms, it's easy to understand why caffeine is an important ingredient in Metabolife 356 for jump-starting your weight-loss efforts.
Ginger root in Metabolife 356
Ginger (Zingiber officinale) is indigenous to tropical Asia and is now cultivated in tropical areas throughout the world. The rhizome, which is technically an underground stem instead of a root, contains oleoresins that are rich in gingerols. These compounds have a variety of sedative effects. Ginger is traditionally used to calm the stomach and as a treatment for motion sickness. Since some individuals experience gastrointestinal upset with caffeine and other stimulatory chemicals, ginger should help to eliminate this occasional Metabolife 356 side effect. Ginger does not have any fat-burning properties.
Siberian ginseng in Metabolife 356
Siberian ginseng (Eleutherococcus senticosis) has a well-deserved reputation as an adaptogen. This means that it helps the body to deal with stress, including the stress caused by a diet and exercise program. Siberian ginseng has been shown to reduce the secretion of cortisol in the adrenal glands. Cortisol is a catabolic hormone that can eat away at muscle tissue, so it is best to keep it under control. Siberian ginseng also promotes the health of the adrenal gland while strengthening the immune system and helping the body fight inflammation. The quantity of Siberian ginseng in this formulation is not indicated.
Chromium picolinate in Metabolife 356
Chromium is a mineral that helps insulin bind to its receptor sites. It is also involved in the metabolism of glucose for energy. A deficiency of chromium can lead to increased fat storage, fatigue, sugar cravings and mood swings, all of which are counterproductive to your weight-loss goals. The average Westerner does not get close to enough chromium, so supplementation is often required. Getting your chromium in a fat burner is as good as buying and consuming it separately.
The picolinate part of the molecule increases the bioavailability of the chromium compared to the pure metal. While there is a lot of propaganda about the supposed advantages of specific carrier molecules, no comparative research has ever been done. All of the commonly available forms of chromium supplements, including the chromium in Metabolife 356, are sufficiently bioavailable to eliminate any deficiency of this mineral that you may have.
Metabolife Results From Other ingredients
The five Metabolife 356 ingredients described so far in this section are the ones that will provide virtually all of the benefit from this product. The remaining nutrients are either unproven or are - in all likelihood - included in such low dosages that they will not burn significant amounts of fat (even if they would have worked if taken in larger quantities). Since the amounts of each nutrient in the proprietary blend are not specified, it is impossible to say for sure.
Lecithin was once popular as a fat-burning agent back before the ephedrine/caffeine blend became popular. It helps to metabolize fatty acids, but this is normally not a limiting factor in fat loss. As a result, you are not likely to experience any benefit from it. Bovine complex is completely ambiguous. It comes from a cow, but what part of the cow is unknown. Even if it's glandular extracts, it's no going to help you burn fat. The spirulina and seven additional herbs in Metabolife 356 have a variety of benefits in promoting general health, as do the vitamins and minerals. However, there is no evidence that they contribute to thermogenesis or fat loss in any appreciable way.
How To Take Metabolife 356 and Metabolife 356 Dosage and Administration
Take 2 Metabolife 356 tablets 2 or 3 times per day on an empty stomach 1 hour before meals. Do not exceed 8 tablets per day.
Metabolife 356 Side Effects
Metabolife 356 Lawsuit and Litigation
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