Miralax (Polyethylene Glycol 3350) is indicated for the treatment of occasional constipation. This product should be used for 2 weeks or less or as directed by a physician.
MiraLax softens the stool and increases the frequency of bowel movements by retaining water in the stool.
The usual Miralax dose is 17 grams (about 1 heaping tablespoon) of powder per day (or as directed by physician) in 8 ounces of water. Each bottle of Miralax is supplied with a measuring cap marked to contain 17 grams of laxative powder when filled to the indicated line. Two to 4 days (48 to 96 hours) may be required to produce a bowel movement.
There have been no reports of accidental Miralax overde. In the event of Miralax overdosage diarrhea would be the expected major event. If an overdose of drug occurred without concomitant ingestion of fluid, dehydration due to diarrhea may result. Medication should be terminated and free water administered. The oral LD50 is >50 gm/ Kg in mice, rats and rabbits.
Patients presenting with complaints of constipation should have a thorough medical history and physical examination to detect associated metabolic, endocrine and neurogenic conditions, and medications. A diagnostic evaluation should include a structural examination of the colon. Patients should be educated about good defecatory and eating habits (such as high fiber diets) and lifestyle changes (adequate dietary fiber and fluid intake, regular exercise) which may produce more regular bowel habits.
Miralax should be administered dissolved in approximately 8 ounces of water.
Miralax is contraindicated in patients with known or suspected bowel obstruction and patients known to be allergic to polyethylene glycol.
Animal reproductive studies have not been performed with Miralax. It is also not known whether Miralax can cause fetal harm when administered to a pregnant woman, or can effect reproductive capacity. MiraLax should only be administered to a pregnant woman if clearly needed.
Store at 25C (77F); excursions permitted to 15-30C (59-86F).