Prempro is an extremely popular drug: 22.3 million prescriptions were written in the U.S. in 2000. However, facts are now emerging that the manufacturer might have overlooked some of the adverse side effects - leading to Prempro litigation.
Prempro Hormone Replacement Therapy ( HRT; Wyeth / American Home Products ) has now been linked to strokes, coronary heart disease (leading to heart attacks), and venous thrombotic embolisms ( blood clots in veins ), the combined risk offsetting the benefits of decrease in colon-rectal cancers and hip fractures (from osteoporosis).