Serzone Ingredients and Composition
Serzone Information
Serzone Ingredients and Composition
Serzone (nefazodone) is an antidepressant for oral administration with a chemical structure unrelated to selective serotonin reuptake inhibitors, tricyclics, tetracyclics, or monoamine oxidase inhibitors (MAOI).
Nefazodone hydrochloride, the active ingredient in Serzone, is a synthetically derived phenylpiperazine antidepressant. The chemical name for nefazodone hydrochloride is 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ether-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one monohydrochloride. The molecular formula is C25H32ClN5O2•HCl, which corresponds to a molecular weight of 506.5.
Nefazodone, the active ingredient in Serzone, is a nonhygroscopic, white crystalline solid. It is freely soluble in chloroform, soluble in propylene glycol, and slightly soluble in polyethylene glycol and water.
Serzone is supplied as hexagonal tablets containing 100 mg, 150 mg, 200 mg, or 250 mg of nefazodone hydrochloride and the following inactive ingredients:
- microcrystalline cellulose
- povidone
- sodium starch glycolate
- colloidal silicon dioxide
- magnesium stearate
- iron oxides (red and/or yellow) as colorants
Serzone Information
