Valdecoxib, the active ingredient in Bextra, is chemically designated as 4-(5-methyl-3-phenyl-4-isox-azolyl) benzenesulfonamide and is a diaryl substituted isoxazole.
The empirical formula for valdecoxib, the active ingredient Bextra, in is C16H14N2O3S,and the molecular weight is 314.36.Valdecoxib is a white crystalline powder that is relatively insoluble in water (10 µg/mL) at 25°C and pH 7.0, soluble in methanol and ethanol, and freely soluble in organic solvents and alkaline (pH=12) aqueous solutions.
Bextra Tablets for oral administration contain either 10 mg or 20mg of valdecoxib. Inactive Bextra ingredients include: