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The side effects sometimes reported while taking Vioxx include weakness or nausea. If they continue or are bothersome, check with your doctor. Notify your physician as soon as possible if you experience itching or skin rash, swelling of the feet or ankles, unexpected weight gain, vomiting material that looks like coffee grounds, or blood in stool or vomit. If you experience swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness; flu-like symptoms; sluggishness; yellowing of the skin or eyes; stomach pain; dark urine or pale stools; or unusual fatigue immediately report these symptoms to your physician.

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