Xenadrine-RFA-1

Xenadrine-RFA-1 Information

Other Names: Xenadrine, Xenadrine EFX, Xenadrine-RFA-1

Xenadrine-RFA-1 is a thermogenic weight loss and bodybuilding drug.

Xenadrine-RFA-1 is one of the largest selling diet-pills on the market. Xenadrine-RFA-1 combines ephedrine, caffeine and the aspirin-like willow bark with Citrus aurantium, ginger root and a nutrient blend that includes L-tyrosine, acetyl-L-carnitine, fisetin, magnesium phosphate and DMAE.

The most active ingredients in Xenadrine-RFA-1 are ephedrine and caffeine. Like other ephedrine/caffeine-based products, Xenadrine-RFA-1 works by inducing thermogenesis (the production of heat), which speeds up your metabolism and burns calories. It also has an appetite-suppressing effect, so you feel less hungry and therefore eat less.

Thus, Xenadrine works on two fronts:

thermogenesis: "speeding up" you metabolism, and making you burn more calories
appetite suppression: making you eat less, and forcing the organism to mobilise the supplies it already posseses - ie. use up fat.

Xenadrine-RFA-1 is manufactured by Cytodyne Technologies.

Xenadrine-RFA-1 Ingredients and Composition

How Does Xenadrine-RFA-1 Work?

The most powerful component in ECA-based supplements is ephedrine. It's long been regarded as a fairly potent thermogenic compound, but it was found to be even more effective when combined with caffeine and aspirin. It's true that caffeine is also a fairly good thermogenic compound, but it hardly measures up to ephedrine.

When these two nutrients are combined in specific ratios - 200 mg caffeine to 20 mg ephedrine - the results are synergistic. In other words, the effects of each are greater than the sum of their individual effects. When aspirin, 300 mg of it per each ephedrine/caffeine dose, is coadministered, the results are further enhanced.

Here is how different Xenadrine ingredients work:

Ephedra in Xenadrine-RFA-1

Ephedrine is the primary fat-burning chemical in the Ephedra sinica plant, often used in from which it gets its name, and is often used in thermogenic weight-loss drugs such as Xenadrine-RFA-1. Also known as ma huang, this plant has a long history of usage in Asian countries for the treatment of asthma and other bronchial conditions. A related chemical, pseudoephedrine, is also found in the plant and is an ingredient in many cold and flu remedies.

Ephedrine is a stimulant that works on the adrenergic receptors of the central nervous system. It has been shown to increase the level of dopamine, which is a precursor to both epinephrine and norepinephrine, which are vital neurotransmitters. Dopamine is also an important neurotransmitter around the hypothalamus, an area of the brain that is important for body arousal. Unlike caffeine, which exerts many of its benefits in muscle tissue, ephedrine appears to work primarily on the central nervous system.

Ephedrine inhibits the reuptake of norepinephrine, a hormone secreted by the medulla of the adrenal glands, that acts as a neurotransmitter. The sympathetic nervous system functions in response to short-term stress; hence norepinephrine increases the heart rate as well as blood pressure. Other actions of norepinephrine include increased glycogenolysis (the conversion of glycogen to glucose) in the liver, increased lipolysis (the conversion of fats to fatty acids) in adipose (fat) tissue, and relaxation of bronchial smooth muscle to open up the air passages to the lungs. All of these actions represent a mobilization of the body's resources in order to meet the stressful challenge; such a response is often termed the 'flight or fight' syndrome.

Basically, ephedra in Xenadrine-RFA-1 keeps your body in 'combat' mode for extended periods of time, facilitating weight loss.

Ephedrine is an effective fat burner on its own, and when it is combined with caffeine, the effects are even greater. While the reasons for this are still not known, it is thought that caffeine has a "permissive" action on ephedrine, lowering the amounts needed to achieve its physiological effects. In other words, caffeine potentiates ephedrine's effect. The E/C studies that showed the greatest benefits used a 10:1 ratio of caffeine to ephedrine. Due to other ingredients and processes targeted, the E/C ratio in Xenadrine-RFA-1 is 8:1.

Caffeine in Xenadrine-RFA-1

The caffeine source in Xenadrine-RFA-1 is guarana seed extract. Guarana is a bushy tree that grows in the Amazon rainforest. Known botanically as Paullina cupana, it is almost as popular as coffee in Brazil. Guarana does not have as much acid as coffee, so it can be less irritating to the stomach than coffee can. Guarana also has epicathechin and proanthocyanidins, both of which are powerful antioxidants that help reduce free-radical damage in cells. Epicathechin is chemically related to epigallocatechin gallate (EGCG), which prolongs the life of norepinephrine. As a result, the epicathechin may keep the thermogenic process going for a even longer period of time, further boosting your metabolic rate and facilitating fat loss.

As far as fat burning is concerned, the primary active ingredient in guarana, used in Xenadrine-RFA-1, is caffeine. This plant chemical is rapidly absorbed by the body and remains in circulation for more than seven hours. Plasma concentrations reach a peak one hour after it is consumed. It is then slowly metabolized, with a half-life of four to six hours.

Caffeine has been shown to dramatically increase free fatty-acid levels, providing the body with a fuel source that it can use instead of the glycogen stored in your liver and muscles. In fact, one study found a 100% increase in plasma free fatty acids after the subjects took 330 mg of caffeine.

At the same time, caffeine has been shown to increase adrenaline levels. This "fight-or-flight" hormone increases alertness and boosts energy levels, helping you to go through your daily tasks with less food intake. Most people experience a reduced appetite when their adrenaline levels are high, usually because they are focused on more essential tasks. With these two mechanisms, it's easy to understand why caffeine is and important Xenadrine-RFA-1 ingredient for jump-starting your weight-loss efforts.

Willow bark extract in Xenadrine-RFA-1

Willow bark is a natural source of salicin, which is similar to the acetylsalicylic acid in aspirin. A traditional pain remedy of the American Indians, this ingredient can further increase the effects of the Xenadrine-RFA-1 ECA stack by helping to raise the body's set point for temperature regulation and keeping the body from re-regulating itself. This boosts the basal metabolic rate and helps to burn more body fat. There does not appear to be any difference between white and purple willow bark.

Citrus aurantium in Xenadrine-RFA-1

Citrus aurantium is the botanical name for a fruit known as zhi shi in traditional Chinese medicine and as bitter orange or sour orange in other countries. The unripe fruit contains synephrine - a chemical that is structurally related to ephedrine - as well as octopamine and tyramine. Like ephedrine, synephrine has the ability to increase metabolic rate and lipolysis (fat breakdown). Synephrine is also a mild appetite suppressant and an energy enhancer. (The Chinese use it to stimulate the Qi, or energy force.) But unlike ephedrine, synephrine has much less impact on the central nervous system. This makes it easier to tolerate for people who are sensitive to ephedrine. The effects of synephrine are greatly increased when it is combined with caffeine. Xenadrine-RFA-1 contains 5 mg of synephrine alkaloids.

L-tyrosine in Xenadrine-RFA-1

L-tyrosine is the amino acid tyrosine in free (unbound) form. Tyrosine is an amino acid that plays an important role in human metabolism. It is the precursor to stimulatory neurotransmitters such as epinephrine, norepinephrine, dopamine and some of the thyroid hormones. All of these neurotransmitters and hormones play important roles in maintaining your metabolic rate. Logically, if you have a greater supply of these precursors, you can nudge your metabolism up a bit, helping you to shed unwanted pounds. Several studies have also shown that tyrosine increases the benefits of caffeine/ephedrine products, in part by curbing appetite. Tyrosine appears to reduce stress and fatigue as well, putting you in a better state of mind and making it easier to stick to your diet and exercise program. The amount of L-tyrosine in Xenadrine-RFA-1 is not indicated on the product label.

Ginger root in Xenadrine-RFA-1

Ginger (Zingiber officinale) is indigenous to tropical Asia and is now cultivated in tropical areas throughout the world. The rhizome, which is technically an underground stem instead of a root, contains oleoresins that are rich in gingerols. These compounds have a variety of sedative effects. Ginger is traditionally used to calm the stomach and as a treatment for motion sickness. Since some individuals experience gastrointestinal upset with caffeine and other stimulatory chemicals, ginger used in Xenadrine-RFA-1 should help to eliminate this occasional side effect. Ginger does not have any fat-burning properties.

Acetyl-L-carnitine in Xenadrine-RFA-1

L-carnitine is a vitamin like compound that facilitates the movement of free-fatty acids to the mitochondria for oxidation through the actions of the enzyme carnitine palmitoyl transferase 1, or CPT-1. This helps to stimulate fat burning. While L-carnitine can be synthesized in the body from the amino acids lysine and methionine, supplementation through Xenadrine-RFA-1 or similar products appears to offer additional benefits.

By consuming carnitine in food (red meat contains relatively large amounts of it) or in supplement form (Xenadrine), you increase the supply of a raw material needed to activate CPT-1, potentially increasing the amount of fat transported into the mitochondria for oxidation. This would also help to maintain liver-glycogen concentrations at higher levels, reducing your appetite.

Acetyl-L-carnitine combines a carnitine molecule with an acetyl molecule. After the body breaks apart this compound, the acetyl group is used to form acetyl-CoA, an important intermediary in the generation of energy from amino acids, fats and proteins. This serves as an energy reservoir and leads to greater levels of the neurotransmitter acetylcholine, which enhances alertness and focus. This could keep you in a more positive state of mind, increasing your willpower as you pursue your Xenadrine-RFA-1 diet program.

Fisetin in Xenadrine-RFA-1

Fisetin is a bioflavonoid that increases the effectiveness of caffeine and Citrus aurantium. It has been shown to mobilize fat-burning enzymes in the fat cells (adipocytes) by acting synergistically with epinephrine on the beta-adrenergic receptors of the fat-cell membrane. Fisetin also has antioxidant properties. Fisetin is a part of the Xenadrine-RFA-1 proprietary blend, and its exact quantity is not specified.

Magnesium phosphate in Xenadrine-RFA-1

Xenadrine-RFA-1 contains magnesium phosphate. This bioavailable source of phosphate helps to increase the level of an essential energy molecule called ATP (adenosine triphosphate) in the liver. Studies have shown that hepatic ATP levels normally decline during a diet, which in turn reduces the availability of the active thyroid hormone T3. The end result is a slower metabolism. Phosphate supplementation promotes a greater level of T3 and therefore a higher metabolic rate, making it easier for you to burn body fat. Magnesium phosphate is a part of the Xenadrine-RFA-1 proprietary blend, and its exact quantity is not specified.

Dimethylaminoethanol (DMAE) in Xenadrine-RFA-1

DMAE (dimethylaminoethanol) is a precursor to choline in the body. This can boost the level of the neurotransmitter acetylcholine in the brain. Unlike many nutrients, DMAE is able to cross the blood-brain barrier. This gives it the potential to enhance attention span and alertness. DMAE supplementation has been shown to increase mental focus and energy levels, which ought to facilitate your adherence to your diet program. DMAE is a part of the Xenadrine-RFA-1 proprietary blend, and its exact quantity is not specified.

How To Take Xenadrine-RFA-1 and Xenadrine-RFA-1 Dosage and Administration

Take 2 Xenadrine-RFA-1 capsules before breakfast and 2 more capsules before your afternoon meal. You could also take 2 capsules before your evening meal for added effect. Do not exceed 6 capsules per day. For best results, begin with half of the recommended Xenadrine-RFA-1 dose (1 capsule two or three times per day) for the first week to assess your tolerance to the formulation.

As with any thermogenic compound, consult your doctor before starting to take it.

Xenadrine-RFA-1 Side Effects

Experiences, Testimonials and Reviews of Xenadrine-RFA-1

Xenadrine-RFA-1 Precautions and Contraindications

As with any thermogenic weight-loss pill, you should consult your doctor before taking Xenadrine-RFA-1, especially if you have a previous history of health problems.

Xenadrine-RFA-1 Clinical Trials and Studies

Storing Xenadrine-RFA-1

Store in a cool and dry place.

Xenadrine-RFA-1 Wholesale and International Shipping

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