Zoloft Side Effects
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Zoloft Side Effects
The most common side effects reported are upset stomach, insomnia, diarrhea, dry mouth, sexual side effects (delayed ejaculation/orgasm), drowsiness, tremor, indigestion, increased sweating, feeling agitated, and decreased appetite.
Less common side effects of Zoloft include:
- Zoloft has been associated with cases of clinically significant hyponatremia (low sodium blood level) in elderly patients.
- Zoloft is associated with a mean decrease in serum uric acid of approximately 7%.The clinical significance of this weak uricosuric effect is unknown.
- During clinical testing in depressed patients, hypomania or mania occurred in approximately 0.6% of Zoloft-treated patients.
- Increased agitation leading to violent behavior.
It is also important to know that:
Many of the SSRIs have been reported by patients to induce agitated, suicidal or homicidal behavior. Pfizer does list agitation and hypomania and/or mania activation as possible side effects of taking Zoloft. Agitation is actually listed by Pfizer as a common adverse reaction to Zoloft. This agitation is what some patients are claiming made them engage in various illegal agitated behaviors including murder. Most disturbing is that many of these types of patients had no prior history of illegal activity or agitation prior to taking Zoloft. The FDA has received many letters from Zoloft patients concerning agitation and other severe adverse effects from taking Zoloft. While the FDA did research the patients' complaints in 1991, no correlation between agitated illegal behavior and Zoloft were found by the FDA .
However, further research and better doctor monitoring of patients taking antidepressant (SSRI in particular) was recommended. Ten years later, the problem still persists, and the FDA has not released any further reports. Many Zoloft patients remain adamant that Zoloft does cause this type of behavior.
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